There are nearly 400 million people with diabetes worldwide, about half are undiagnosed16. A preclinical study showed that untreated diabetes mellitus has negative effects on the early osseointegration of dental implants. SLActive® accelerated the osseointegration of dental implants suggesting that a better prognosis for implant treatment in diabetic conditions is possible. SLActive® Implants showed a significantly higher BIC and higher peri-implant bone density compared to hydrophobic implants.17
It is estimated that over 200 million people worldwide are suffering from osteoporosis.18 Osteoporosis can compromise the bone formation. Using the SLActive® surface may promote bone healing and osseointegration in an osteoporotic situation according to a preclinical study.19
The average age of the world population is rapidly increasing. Until 2050, the population over 60 will double (from 11 % in 2000 to 22 %, WHO)20. The population over 65 with severely resorbed mandibles will increase to 17 % in Europe by 2030, and to 25 % in the US by 2050 21,22. The 5-year data of a multicenter study with the 4 mm Straumann® Standard Plus Short Implants and SLActive® restored with Fixed Dental Prostheses (FDPs) in severely resorbed posterior mandibles showed a high survival rate of 94 % and minimal marginal bone loss (MBL). This result supports that SP Short Implants with the SLActive® surface can be used in FDPs in severely atrophic mandibles without the need for bone augmentation.23
16 International Diabetes Federation. http://www.idf.org/diabetesatlas/ 17 Schlegel KA, Prechtl C, Möst T, Seidl C, Lutz R, von Wilmowsky C. Osseointegration of SLActive® implants in diabetic pigs Clin Oral Implants Res. 2013 Feb;24 (2):128-34. 18 Reginster JY, Burlet N. Osteoporosis: a still increasing prevalence. Bone. 2006 Feb;38(2 Suppl 1):S4-9. 19 Mardas N, Schwarz F, Petrie A, Hakimi AR, Donos N. The effect of SLActive® surface in guided bone formation in osteoporotic-like conditions Clin Oral Implants Res. 2011 Apr;22(4):406-15. 20 WHO: http://www.who.int/ageing/about/facts/en/index.html 21 *iData Report , Dental Implants and Final Abutments, Europe 2012 22 iData Report , Dental Implants and Final Abutments, USA 2012 23 Slotte Christer et al, Four-mm implants supporting fixed partial dentures in the posterior mandible. 5-year results from a multicenter study. Presented at the 20th Annual Scientific Meeting of the European Association of Osseointegration, 10-13 October 2012, Copenhagen, Denmark.
Precaution: Special attention should be given to patients who have local or systemic factors that could interfere with the healing process. For further informaiton please read Straumann instruction for use.